The epidemic of 2019-novel-coronavirus (2019-nCoV) pneumonia and insights for emerging infectious diseases in the future.
Identifieur interne : 000115 ( new/Analysis ); précédent : 000114; suivant : 000116The epidemic of 2019-novel-coronavirus (2019-nCoV) pneumonia and insights for emerging infectious diseases in the future.
Auteurs : Jin-Yan Li [République populaire de Chine] ; Zhi You [République populaire de Chine] ; Qiong Wang [République populaire de Chine] ; Zhi-Jian Zhou [République populaire de Chine] ; Ye Qiu [République populaire de Chine] ; Rui Luo [République populaire de Chine] ; Xing-Yi Ge [République populaire de Chine]Source :
- Microbes and infection [ 1769-714X ] ; 2020.
Descripteurs français
- KwdFr :
- Antiviraux (usage thérapeutique), Chine (épidémiologie), Génome viral, Humains, Infections à coronavirus (), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Maladies transmissibles émergentes (virologie), Maladies transmissibles émergentes (épidémiologie), Phylogénie, Pneumopathie virale (), Pneumopathie virale (transmission), Pneumopathie virale (épidémiologie), Récepteurs viraux, Tropisme viral, Épidémies.
- MESH :
- usage thérapeutique : Antiviraux, Infections à coronavirus, Pneumopathie virale.
- virologie : Maladies transmissibles émergentes.
- épidémiologie : Chine, Infections à coronavirus, Maladies transmissibles émergentes, Pneumopathie virale.
- Génome viral, Humains, Infections à coronavirus, Phylogénie, Pneumopathie virale, Récepteurs viraux, Tropisme viral, Épidémies.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- Antiviral Agents (therapeutic use), Betacoronavirus (genetics), Betacoronavirus (pathogenicity), China (epidemiology), Communicable Diseases, Emerging (epidemiology), Communicable Diseases, Emerging (virology), Coronavirus Infections (epidemiology), Coronavirus Infections (prevention & control), Coronavirus Infections (therapy), Coronavirus Infections (transmission), Epidemics, Genome, Viral, Humans, Phylogeny, Pneumonia, Viral (epidemiology), Pneumonia, Viral (prevention & control), Pneumonia, Viral (therapy), Pneumonia, Viral (transmission), Receptors, Virus, Viral Tropism.
- MESH :
- chemical , therapeutic use : Antiviral Agents.
- geographic , epidemiology : China.
- epidemiology : Communicable Diseases, Emerging, Coronavirus Infections, Pneumonia, Viral.
- genetics : Betacoronavirus.
- pathogenicity : Betacoronavirus.
- prevention & control : Coronavirus Infections, Pneumonia, Viral.
- therapy : Coronavirus Infections, Pneumonia, Viral.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- virology : Communicable Diseases, Emerging.
- Epidemics, Genome, Viral, Humans, Phylogeny, Receptors, Virus, Viral Tropism.
Abstract
At the end of December 2019, a novel coronavirus, 2019-nCoV, caused an outbreak of pneumonia spreading from Wuhan, Hubei province, to the whole country of China, which has posed great threats to public health and attracted enormous attention around the world. To date, there are no clinically approved vaccines or antiviral drugs available for these human coronavirus infections. Intensive research on the novel emerging human infectious coronaviruses is urgently needed to elucidate their route of transmission and pathogenic mechanisms, and to identify potential drug targets, which would promote the development of effective preventive and therapeutic countermeasures. Herein, we describe the epidemic and etiological characteristics of 2019-nCoV, discuss its essential biological features, including tropism and receptor usage, summarize approaches for disease prevention and treatment, and speculate on the transmission route of 2019-nCoV.
DOI: 10.1016/j.micinf.2020.02.002
PubMed: 32087334
Affiliations:
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pubmed:32087334Le document en format XML
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To date, there are no clinically approved vaccines or antiviral drugs available for these human coronavirus infections. Intensive research on the novel emerging human infectious coronaviruses is urgently needed to elucidate their route of transmission and pathogenic mechanisms, and to identify potential drug targets, which would promote the development of effective preventive and therapeutic countermeasures. Herein, we describe the epidemic and etiological characteristics of 2019-nCoV, discuss its essential biological features, including tropism and receptor usage, summarize approaches for disease prevention and treatment, and speculate on the transmission route of 2019-nCoV.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Li, Jin Yan" sort="Li, Jin Yan" uniqKey="Li J" first="Jin-Yan" last="Li">Jin-Yan Li</name></noRegion><name sortKey="Ge, Xing Yi" sort="Ge, Xing Yi" uniqKey="Ge X" first="Xing-Yi" last="Ge">Xing-Yi Ge</name><name sortKey="Luo, Rui" sort="Luo, Rui" uniqKey="Luo R" first="Rui" last="Luo">Rui Luo</name><name sortKey="Qiu, Ye" sort="Qiu, Ye" uniqKey="Qiu Y" first="Ye" last="Qiu">Ye Qiu</name><name sortKey="Wang, Qiong" sort="Wang, Qiong" uniqKey="Wang Q" first="Qiong" last="Wang">Qiong Wang</name><name sortKey="You, Zhi" sort="You, Zhi" uniqKey="You Z" first="Zhi" last="You">Zhi You</name><name sortKey="Zhou, Zhi Jian" sort="Zhou, Zhi Jian" uniqKey="Zhou Z" first="Zhi-Jian" last="Zhou">Zhi-Jian Zhou</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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